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It also discusses the key obstacles that must be overcome in the translation of these technologies from preclinical research to clinical implementation

(2)], we predicted inhibition of mitochondrial 3-keto-acyl-CoA thiolase activity

doi: 10.1007/978-1-4684-5730-8_11

This combination exhibits protumorigenic effects and induces metabolic reprogramming, leading to an increase in formate production and the metabolism of glutamine (145)